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In vivo inhibition of the mitochondrial H(+)-ATP synthase in neurons promotes metabolic preconditioning

A key transducer in energy conservation and signaling cell death is the mitochondrial H(+)-ATP synthase. The expression of the ATPase inhibitory factor 1 (IF1) is a strategy used by cancer cells to inhibit the activity of the H(+)-ATP synthase to generate a ROS signal that switches on cellular progr...

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Detalhes bibliográficos
Main Authors: Formentini, Laura, Pereira, Marta P, Sánchez-Cenizo, Laura, Santacatterina, Fulvio, Lucas, José J, Navarro, Carmen, Martínez-Serrano, Alberto, Cuezva, José M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000092/
https://ncbi.nlm.nih.gov/pubmed/24521670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386392
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