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A Review of the Inhibition of the Mitochondrial ATP Synthase by IF1 in vivo: Reprogramming Energy Metabolism and Inducing Mitohormesis

The ATPase Inhibitory Factor 1 (IF1) is the physiological inhibitor of the mitochondrial ATP synthase. Herein, we summarize the regulation of the expression and activity of IF1 as a main driver of the activity of oxidative phosphorylation (OXPHOS) in mammalian tissues. We emphasize that the expressi...

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Udgivet i:Front Physiol
Main Authors: García-Aguilar, Ana, Cuezva, José M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156145/
https://ncbi.nlm.nih.gov/pubmed/30283362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01322
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