Establishment of an Invasive Prostate Cancer Model in Transgenic Rats by Intermittent Testosterone Administration

We have established a transgenic rat for adenocarcinoma of the prostate (TRAP) model that features uniform adenocarcinoma development in prostatic lobes at high incidence within a short experimental period. However, no invasive carcinomas with reactive stroma characteristics similar to those in man...

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Bibliographic Details
Main Authors: Sato, Shinya, Suzuki, Shugo, Naiki-Ito, Aya, Komiya, Masami, Ne, Long, Kato, Hiroyuki, Sagawa, Hiroyuki, Yamashita, Yoriko, Shirai, Tomoyuki, Takahashi, Satoru
Format: Artigo
Language:Inglês
Published: Japanese Society of Toxicologic Pathology 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000072/
https://ncbi.nlm.nih.gov/pubmed/24791066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2013-0052
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