The Ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation

The severe defects in growth plate development caused by chondrocyte extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) gain or loss-of-function suggest that tight spatial and temporal regulation of mitogen-activated protein kinase signaling is necessary to achieve harmonious growth pla...

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Main Authors: Ono, Koichiro, Karolak, Matthew R., Ndong, Jean de la Croix, Wang, Weixi, Yang, Xiangli, Elefteriou, Florent
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999379/
https://ncbi.nlm.nih.gov/pubmed/23571107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt162
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