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Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription
Activating transcription factor 4 (Atf4) is a leucine-zipper-containing protein of the cAMP response element-binding protein (CREB) family. Ablation of Atf4 (Atf4(−/−)) in mice leads to severe skeletal defects, including delayed ossification and low bone mass, short stature and short limbs. Atf4 is...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781050/ https://ncbi.nlm.nih.gov/pubmed/19906842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.043281 |
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