Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh

Atf4 is a leucine zipper-containing transcription factor that activates osteocalcin (Ocn) in osteoblasts and indian hedgehog (Ihh) in chondrocytes. The relative contribution of Atf4 in chondrocytes and osteoblasts to the regulation of skeletal development and bone formation is poorly understood. Inv...

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Autori principali: Wang, Weiguang, Lian, Na, Ma, Yun, Li, Lingzhen, Gallant, Richard C., Elefteriou, Florent, Yang, Xiangli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252356/
https://ncbi.nlm.nih.gov/pubmed/22190639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.069575
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