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Investigating the Reactivities of a Polyketide Synthase Module through Fluorescent Click Chemistry

A method for monitoring in vitro polyketide synthesis has been developed whereby nonchromophoric polyketide products are made brightly fluorescent in a simple, rapid, inexpensive, and bioorthogonal manner through CuAAC with sulforhodamine B azide.

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Detalhes bibliográficos
Main Authors: Hughes, Amanda Jane, Tibby, Matthew R., Wagner, Drew T., Brantley, Johnathan N., Keatinge-Clay, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999232/
https://ncbi.nlm.nih.gov/pubmed/24196586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc47513a
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