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Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint

The mitotic checkpoint monitors kinetochore–microtubule attachment and prevents anaphase until all kinetochores are stably attached. Checkpoint regulation hinges on the dynamic localization of checkpoint proteins to kinetochores. Unattached, checkpoint-active kinetochores accumulate multiple checkpo...

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Bibliografske podrobnosti
Main Authors: Ballister, Edward R., Riegman, Michelle, Lampson, Michael A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998811/
https://ncbi.nlm.nih.gov/pubmed/24637323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311113
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