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Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint
The mitotic checkpoint monitors kinetochore–microtubule attachment and prevents anaphase until all kinetochores are stably attached. Checkpoint regulation hinges on the dynamic localization of checkpoint proteins to kinetochores. Unattached, checkpoint-active kinetochores accumulate multiple checkpo...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3998811/ https://ncbi.nlm.nih.gov/pubmed/24637323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311113 |
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