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Transcriptomic changes in the frontal cortex associated with paternal age

BACKGROUND: Advanced paternal age is robustly associated with several human neuropsychiatric disorders, particularly autism. The precise mechanism(s) mediating the paternal age effect are not known, but they are thought to involve the accumulation of de novo (epi)genomic alterations. In this study w...

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Autors principals: Smith, Rebecca G, Fernandes, Cathy, Kember, Rachel, Schalkwyk, Leonard C, Buxbaum, Joseph, Reichenberg, Abraham, Mill, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998024/
https://ncbi.nlm.nih.gov/pubmed/24655730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-24
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