Advanced paternal age effects in neurodevelopmental disorders—review of potential underlying mechanisms

Multiple epidemiological studies suggest a relationship between advanced paternal age (APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly with regard to increased risk for autism and schizophrenia. Conclusive evidence about how age-related changes in paternal gamet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Janecka, M, Mill, J, Basson, M A, Goriely, A, Spiers, H, Reichenberg, A, Schalkwyk, L, Fernandes, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299396/
https://ncbi.nlm.nih.gov/pubmed/28140401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.294
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