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Transcriptomic changes in the frontal cortex associated with paternal age

BACKGROUND: Advanced paternal age is robustly associated with several human neuropsychiatric disorders, particularly autism. The precise mechanism(s) mediating the paternal age effect are not known, but they are thought to involve the accumulation of de novo (epi)genomic alterations. In this study w...

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Detalhes bibliográficos
Main Authors: Smith, Rebecca G, Fernandes, Cathy, Kember, Rachel, Schalkwyk, Leonard C, Buxbaum, Joseph, Reichenberg, Abraham, Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998024/
https://ncbi.nlm.nih.gov/pubmed/24655730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-24
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