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Transcriptomic changes in the frontal cortex associated with paternal age

BACKGROUND: Advanced paternal age is robustly associated with several human neuropsychiatric disorders, particularly autism. The precise mechanism(s) mediating the paternal age effect are not known, but they are thought to involve the accumulation of de novo (epi)genomic alterations. In this study w...

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Main Authors: Smith, Rebecca G, Fernandes, Cathy, Kember, Rachel, Schalkwyk, Leonard C, Buxbaum, Joseph, Reichenberg, Abraham, Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998024/
https://ncbi.nlm.nih.gov/pubmed/24655730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-24
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