Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model

BACKGROUND: Accumulating evidence from epidemiological research has demonstrated an association between advanced paternal age and risk for several psychiatric disorders including autism, schizophrenia and early-onset bipolar disorder. In order to establish causality, this study used an animal model...

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Autori principali: Smith, Rebecca G., Kember, Rachel L., Mill, Jonathan, Fernandes, Cathy, Schalkwyk, Leonard C., Buxbaum, Joseph D., Reichenberg, Abraham
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794376/
https://ncbi.nlm.nih.gov/pubmed/20041141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008456
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