Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T(H1) Adaptive Immunity

BACKGROUND: Atherosclerotic lesions grow via the accumulation of leukocytes and oxidized lipoproteins in the vessel wall. Leukocytes can attenuate or augment atherosclerosis through the release of cytokines, chemokines, and other mediators. Deciphering how leukocytes develop, oppose and complement e...

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Autori principali: Hilgendorf, Ingo, Theurl, Igor, Gerhardt, Louisa M.S., Robbins, Clinton S., Weber, Georg F., Gonen, Ayelet, Iwamoto, Yoshiko, Degousee, Norbert, Holderried, Tobias A. W., Winter, Carla, Zirlik, Andreas, Lin, Herbert Y., Sukhova, Galina K., Butany, Jagdish, Rubin, Barry B., Witztum, Joseph L., Libby, Peter, Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997655/
https://ncbi.nlm.nih.gov/pubmed/24488984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.006381
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