Innate Response Activator B Cells Protect Against Microbial Sepsis

Recognition and clearance of bacterial infection is a fundamental property of innate immunity. Here we describe an effector B cell population that protects against microbial sepsis. Innate response activator (IRA)-B cells are phenotypically and functionally distinct, develop and diverge from B1a B c...

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Autors principals: Rauch, Philipp J., Chudnovskiy, Aleksey, Robbins, Clinton S., Weber, Georg F., Etzrodt, Martin, Hilgendorf, Ingo, Tiglao, Elizabeth, Figueiredo, Jose-Luiz, Iwamoto, Yoshiko, Theurl, Igor, Gorbatov, Rostic, Waring, Michael T., Chicoine, Adam T., Mouded, Majd, Pittet, Mikael J., Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279743/
https://ncbi.nlm.nih.gov/pubmed/22245738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1215173
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