Extramedullary Hematopoiesis Generates Ly-6C(high) Monocytes that Infiltrate Atherosclerotic Lesions

BACKGROUND: Atherosclerotic lesions are believed to grow via the recruitment of bone marrow-derived monocytes. Among the known murine monocyte subsets, Ly-6C(high) monocytes are inflammatory, accumulate in lesions preferentially, and differentiate. Here we hypothesized that the bone marrow outsource...

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Main Authors: Robbins, Clinton S., Chudnovskiy, Aleksey, Rauch, Philipp J., Figueiredo, Jose-Luiz, Iwamoto, Yoshiko, Gorbatov, Rostic, Etzrodt, Martin, Weber, Georg F., Ueno, Takuya, van Rooijen, Nico, Mulligan-Kehoe, Mary Jo, Libby, Peter, Nahrendorf, Matthias, Pittet, Mikael J., Weissleder, Ralph, Swirski, Filip K.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263762/
https://ncbi.nlm.nih.gov/pubmed/22144566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.061986
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