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Chromogranin A is a T Cell Antigen in Human Type 1 Diabetes

Chromogranin A (ChgA) is a beta cell secretory granule protein and a peptide of ChgA, WE14, was recently identified as a ligand for diabetogenic CD4 T cell clones derived from the NOD mouse. In this study we compared responses of human CD4 T cells from recent onset type 1 diabetic (T1D) and control...

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Detalhes bibliográficos
Main Authors: Gottlieb, Peter A, Delong, Thomas, Baker, Rocky L., Fitzgerald-Miller, Lisa, Wagner, Rebecca, Cook, Gabrielle, Rewers, Marian R., Michels, Aaron, Haskins, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995825/
https://ncbi.nlm.nih.gov/pubmed/24239002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.10.003
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