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Granulopoiesis Requires Increased C/EBPα Compared to Monopoiesis, Correlated with Elevated Cebpa in Immature G-CSF Receptor versus M-CSF Receptor Expressing Cells

C/EBPα is required for the formation of granulocyte-monocyte progenitors; however, its role in subsequent myeloid lineage specification remains uncertain. Transduction of murine marrow with either of two Cebpa shRNAs markedly increases monocyte and reduces granulocyte colonies in methylcellulose or...

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Autori principali: Ma, Ou, Hong, SunHwa, Guo, Hong, Ghiaur, Gabriel, Friedman, Alan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994156/
https://ncbi.nlm.nih.gov/pubmed/24752325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095784
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