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Enhanced Tumor Delivery of Gemcitabine via PEG-DSPE/TPGS Mixed Micelles

[Image: see text] Gemcitabine is a potent anticancer drug approved for the treatment of pancreatic, non-small-cell lung, breast, and ovarian cancers. The major deficiencies of current gemcitabine therapy, however, are its rapid metabolic inactivation and narrow therapeutic window. Herein, we employe...

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Detalhes bibliográficos
Main Authors: Wang, Yingzhe, Fan, Wei, Dai, Xin, Katragadda, Usha, Mckinley, DeAngelo, Teng, Quincy, Tan, Chalet
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993932/
https://ncbi.nlm.nih.gov/pubmed/24579673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4005904
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