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Improved Total Synthesis and Biological Evaluation of Potent Apratoxin S4 Based Anticancer Agents with Differential Stability and Further Enhanced Activity

[Image: see text] Apratoxins are cytotoxic natural products originally isolated from marine cyanobacteria that act by preventing cotranslational translocation early in the secretory pathway to downregulate receptor levels and inhibit growth factor secretion, leading to potent antiproliferative activ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chen, Qi-Yin, Liu, Yanxia, Cai, Weijing, Luesch, Hendrik
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2014
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993931/
https://ncbi.nlm.nih.gov/pubmed/24660812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4019965
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