Defect of CARD9 Leads to Impaired Accumulation of Gamma Interferon-Producing Memory Phenotype T Cells in Lungs and Increased Susceptibility to Pulmonary Infection with Cryptococcus neoformans

Caspase recruitment domain-containing protein 9 (CARD9) is an adaptor molecule signal that is critical for NF-κB activation and is triggered through C-type lectin receptors (CLRs), which are pattern recognition receptors that recognize carbohydrate structures. Previous studies have reported that Cry...

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Autori principali: Yamamoto, Hideki, Nakamura, Yuri, Sato, Ko, Takahashi, Yurie, Nomura, Toshiki, Miyasaka, Tomomitsu, Ishii, Keiko, Hara, Hiromitsu, Yamamoto, Natsuo, Kanno, Emi, Iwakura, Yoichiro, Kawakami, Kazuyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993402/
https://ncbi.nlm.nih.gov/pubmed/24470469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01089-13
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