Novel Toll-Like Receptor 9 Agonist Derived from Cryptococcus neoformans Attenuates Allergic Inflammation Leading to Asthma Onset in Mice

INTRODUCTION: The enhanced type 2 helper (Th2) immune response is responsible for the pathogenesis of allergic asthma. To suppress the enhanced Th2 immune response, activation of the Th1 immune response has been an alternative strategy for anti-asthma therapy. In this context, effective Th1-inducing...

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Udgivet i:Int Arch Allergy Immunol
Main Authors: Dobashi-Okuyama, Kaori, Kawakami, Kazuyoshi, Miyasaka, Tomomitsu, Sato, Ko, Ishii, Keiko, Kawakami, Kaori, Masuda, Chiaki, Suzuki, Syugo, Kasamatsu, Jun, Yamamoto, Hideki, Tanno, Daiki, Kanno, Emi, Tanno, Hiromasa, Kawano, Tasuku, Takayanagi, Motoaki, Takahashi, Tomoko, Ohno, Isao
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2020
Fag:
Experimental Allergy − Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592942/
https://ncbi.nlm.nih.gov/pubmed/32585675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000508535
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