Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms

Constitutive activation of NF-κB is a hallmark of the activated B cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL), owing to upstream signals from the B cell receptor (BCR) and MyD88 pathways. The linear polyubiquitin chain assembly complex (LUBAC) attaches linear polyubiquitin chain...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Yibin, Schmitz, Roland, Mitala, Joseph, Whiting, Amanda, Xiao, Wenming, Ceribelli, Michele, Wright, George W., Zhao, Hong, Yang, Yandan, Xu, Weihong, Rosenwald, Andreas, Ott, German, Gascoyne, Randy D., Connors, Joseph M., Rimsza, Lisa M., Campo, Elias, Jaffe, Elaine S., Delabie, Jan, Smeland, Erlend B., Braziel, Rita M., Tubbs, Raymond R., Cook, James. R., Weisenburger, Dennis D., Chan, Wing C., Wiestner, Adrian, Kruhlak, Michael J., Iwai, Kazuhiro, Bernal, Federico, Staudt, Louis M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992927/
https://ncbi.nlm.nih.gov/pubmed/24491438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0915
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