Loss of signaling via Gα13 in germinal center B cell-derived lymphoma

Germinal center (GC) B cell-like diffuse large B cell lymphoma (GCB-DLBCL) is a common malignancy yet the signaling pathways deregulated and the factors leading to its systemic dissemination are poorly defined(1,2). Work in mice showed that sphingosine-1-phosphate receptor-2 (S1PR2), a Gα12 and Gα13...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Muppidi, Jagan R., Schmitz, Roland, Green, Jesse A., Xiao, Wenming, Larsen, Adrien B., Braun, Sterling E., An, Jinping, Xu, Ying, Rosenwald, Andreas, Ott, German, Gascoyne, Randy D., Rimsza, Lisa M., Campo, Elias, Jaffe, Elaine S., Delabie, Jan, Smeland, Erlend B., Braziel, Rita M., Tubbs, Raymond R., Cook, J. R., Weisenburger, Dennis D., Chan, Wing C., Vaidehi, Nagarajan, Staudt, Louis M., Cyster, Jason G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267955/
https://ncbi.nlm.nih.gov/pubmed/25274307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13765
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