Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome

The 26S proteasome is a 2.5 MDa molecular machine that executes the degradation of substrates of the ubiquitin–proteasome pathway. The molecular architecture of the 26S proteasome was recently established by cryo-EM approaches. For a detailed understanding of the sequence of events from the initial...

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Detaylı Bibliyografya
Asıl Yazarlar: Unverdorben, Pia, Beck, Florian, Śledź, Paweł, Schweitzer, Andreas, Pfeifer, Günter, Plitzko, Jürgen M., Baumeister, Wolfgang, Förster, Friedrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992697/
https://ncbi.nlm.nih.gov/pubmed/24706844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403409111
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