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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
The 26S proteasome is a 2.5 MDa molecular machine that executes the degradation of substrates of the ubiquitin–proteasome pathway. The molecular architecture of the 26S proteasome was recently established by cryo-EM approaches. For a detailed understanding of the sequence of events from the initial...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992697/ https://ncbi.nlm.nih.gov/pubmed/24706844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403409111 |
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