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Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype
Polycystic ovary syndrome (PCOS), characterized by increased ovarian androgen biosynthesis, anovulation, and infertility, affects 5–7% of reproductive-age women. Genome-wide association studies identified PCOS candidate loci that were replicated in subsequent reports, including DENND1A, which encode...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992676/ https://ncbi.nlm.nih.gov/pubmed/24706793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400574111 |
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