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Cholesterol Side-Chain Cleavage Gene Expression in Theca Cells: Augmented Transcriptional Regulation and mRNA Stability in Polycystic Ovary Syndrome

Hyperandrogenism is characteristic of women with polycystic ovary syndrome (PCOS). Ovarian theca cells isolated from PCOS follicles and maintained in long-term culture produce elevated levels of progestins and androgens compared to normal theca cells. Augmented steroid production in PCOS theca cells...

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書誌詳細
主要な著者: Wickenheisser, Jessica K., Biegler, Jessica M., Nelson-DeGrave, Velen L., Legro, Richard S., Strauss, Jerome F., McAllister, Jan M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498373/
https://ncbi.nlm.nih.gov/pubmed/23155436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048963
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