PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women

Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of 3′,5′-cyclic adenosine monophosphate (cAMP). cAMP signaling pathways are controlled through regulation of its synthesis by adenylyl cyclases, and cA...

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Bibliografiske detaljer
Main Authors: Chen, Chen, Wickenheisser, Jessica, Ewens, Kathryn G., Ankener, Wendy, Legro, Richard S., Dunaif, Andrea, McAllister, Jan M., Spielman, Richard S., Strauss, Jerome F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709315/
https://ncbi.nlm.nih.gov/pubmed/19482904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gap035
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