PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women

Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of 3′,5′-cyclic adenosine monophosphate (cAMP). cAMP signaling pathways are controlled through regulation of its synthesis by adenylyl cyclases, and cA...

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Detalhes bibliográficos
Main Authors: Chen, Chen, Wickenheisser, Jessica, Ewens, Kathryn G., Ankener, Wendy, Legro, Richard S., Dunaif, Andrea, McAllister, Jan M., Spielman, Richard S., Strauss, Jerome F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709315/
https://ncbi.nlm.nih.gov/pubmed/19482904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gap035
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