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PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women

Polycystic ovary syndrome (PCOS) is characterized by excessive theca cell androgen secretion, dependent upon LH, which acts through the intermediacy of 3′,5′-cyclic adenosine monophosphate (cAMP). cAMP signaling pathways are controlled through regulation of its synthesis by adenylyl cyclases, and cA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chen, Wickenheisser, Jessica, Ewens, Kathryn G., Ankener, Wendy, Legro, Richard S., Dunaif, Andrea, McAllister, Jan M., Spielman, Richard S., Strauss, Jerome F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709315/
https://ncbi.nlm.nih.gov/pubmed/19482904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gap035
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