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Polymorphisms in the SHBG Gene Influence Serum SHBG Levels in Women with Polycystic Ovary Syndrome

CONTEXT: Single-nucleotide polymorphisms (SNPs) in the SHBG gene are associated with type 2 diabetes mellitus. SHBG has also been proposed as a candidate gene for the polycystic ovary syndrome (PCOS). OBJECTIVE: The study aims were 1) to determine whether any of four SHBG SNPs (rs1779941, rs6297, rs...

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Autors principals: Wickham, Edmond P., Ewens, Kathryn G., Legro, Richard S., Dunaif, Andrea, Nestler, John E., Strauss, Jerome F.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070246/
https://ncbi.nlm.nih.gov/pubmed/21252242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1842
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