FTO and MC4R Gene Variants Are Associated with Obesity in Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in women. It is also associated with metabolic disturbances that place women at increased risk for obesity and type 2 diabetes. There is strong evidence for familial clustering of PCOS and a genetic predisposition. Howe...

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Autors principals: Ewens, Kathryn G., Jones, Michelle R., Ankener, Wendy, Stewart, Douglas R., Urbanek, Margrit, Dunaif, Andrea, Legro, Richard S., Chua, Angela, Azziz, Ricardo, Spielman, Richard S., Goodarzi, Mark O., Strauss, Jerome F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024473/
https://ncbi.nlm.nih.gov/pubmed/21283731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016390
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