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Microtubule binding distinguishes dystrophin from utrophin
Dystrophin and utrophin are highly similar proteins that both link cortical actin filaments with a complex of sarcolemmal glycoproteins, yet localize to different subcellular domains within normal muscle cells. In mdx mice and Duchenne muscular dystrophy patients, dystrophin is lacking and utrophin...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992671/ https://ncbi.nlm.nih.gov/pubmed/24706788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323842111 |
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