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Microtubule binding distinguishes dystrophin from utrophin

Dystrophin and utrophin are highly similar proteins that both link cortical actin filaments with a complex of sarcolemmal glycoproteins, yet localize to different subcellular domains within normal muscle cells. In mdx mice and Duchenne muscular dystrophy patients, dystrophin is lacking and utrophin...

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Detalhes bibliográficos
Main Authors: Belanto, Joseph J., Mader, Tara L., Eckhoff, Michael D., Strandjord, Dana M., Banks, Glen B., Gardner, Melissa K., Lowe, Dawn A., Ervasti, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992671/
https://ncbi.nlm.nih.gov/pubmed/24706788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323842111
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