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Dystrophin and utrophin have distinct effects on the structural dynamics of actin
We have used time-resolved spectroscopy to investigate the structural dynamics of actin interaction with dystrophin and utrophin in relationship to the pathology of muscular dystrophy. Dystrophin and utrophin bind actin in vitro with similar affinities, but the molecular contacts of these two protei...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683112/ https://ncbi.nlm.nih.gov/pubmed/19416869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812007106 |
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