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Dystrophin and utrophin have distinct effects on the structural dynamics of actin
We have used time-resolved spectroscopy to investigate the structural dynamics of actin interaction with dystrophin and utrophin in relationship to the pathology of muscular dystrophy. Dystrophin and utrophin bind actin in vitro with similar affinities, but the molecular contacts of these two protei...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683112/ https://ncbi.nlm.nih.gov/pubmed/19416869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812007106 |
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