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Functional Substitution by TAT-Utrophin in Dystrophin-Deficient Mice
BACKGROUND: The loss of dystrophin compromises muscle cell membrane stability and causes Duchenne muscular dystrophy and/or various forms of cardiomyopathy. Increased expression of the dystrophin homolog utrophin by gene delivery or pharmacologic up-regulation has been demonstrated to restore membra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680620/ https://ncbi.nlm.nih.gov/pubmed/19478831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1000083 |
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