Heat shock protein 90 controls HIV-1 reactivation from latency

Latency allows HIV-1 to persist in long-lived cellular reservoirs, preventing virus eradication. We have previously shown that the heat shock protein 90 (Hsp90) is required for HIV-1 gene expression and mediates greater HIV-1 replication in conditions of hyperthermia. Here we report that specific in...

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Detalhes bibliográficos
Main Authors: Anderson, Ian, Low, Jun Siong, Weston, Stuart, Weinberger, Michael, Zhyvoloup, Alexander, Labokha, Aksana A., Corazza, Gianmarco, Kitson, Russell A., Moody, Christopher J., Marcello, Alessandro, Fassati, Ariberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992654/
https://ncbi.nlm.nih.gov/pubmed/24706778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320178111
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