Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, with and without a Family History of Cancer

We studied 2332 individuals with monoallelic mutations in MUTYH among 9504 relatives of 264 colorectal cancer (CRC) cases with a MUTYH mutation. We estimated CRC risks, through 70 y of age, of 7.2% for male carriers of monoallelic mutations (95% confidence interval [CI], 4.6%–11.3%) and 5.6% for fem...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Win, Aung Ko, Dowty, James G., Cleary, Sean P., Kim, Hyeja, Buchanan, Daniel D., Young, Joanne P., Clendenning, Mark, Rosty, Christophe, MacInnis, Robert J., Giles, Graham G., Boussioutas, Alex, Macrae, Finlay A., Parry, Susan, Goldblatt, Jack, Baron, John A., Burnett, Terrilea, Marchand, Loïc Le, Newcomb, Polly A., Haile, Robert W., Hopper, John L., Cotterchio, Michelle, Gallinger, Steven, Lindor, Noralane M., Tucker, Katherine M., Winship, Ingrid M., Jenkins, Mark A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992182/
https://ncbi.nlm.nih.gov/pubmed/24444654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.01.022
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