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Inflammation-Inducible Type 2 Deiodinase Expression in the Leptomeninges, Choroid Plexus, and at Brain Blood Vessels in Male Rodents

Thyroid hormone regulates immune functions and has antiinflammatory effects. In promoter assays, the thyroid hormone-activating enzyme, type 2 deiodinase (D2), is highly inducible by the inflammatory transcription factor nuclear factor-κ B (NF-κB), but it is unknown whether D2 is induced in a simila...

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Autors principals: Wittmann, Gábor, Harney, John W., Singru, Praful S., Nouriel, Shira S., Reed Larsen, P., Lechan, Ronald M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990842/
https://ncbi.nlm.nih.gov/pubmed/24601886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2154
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