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A Targeted Proteomics Approach for Profiling Murine Cytochrome P450 Expression

The cytochrome P450 (P450) superfamily of enzymes plays a prominent role in drug metabolism. Although mice are a widely used preclinical model in pharmacology, the expression of murine P450 enzymes at the protein level has yet to be fully defined. Twenty-seven proteins belonging to P450 subfamilies...

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Detalhes bibliográficos
Main Authors: Hersman, Elisabeth M., Bumpus, Namandjé N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989799/
https://ncbi.nlm.nih.gov/pubmed/24594750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.212456
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