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Albumin-bound fatty acids but not albumin itself alter redox balance in tubular epithelial cells and induce a peroxide-mediated redox-sensitive apoptosis

Albuminuria is associated with metabolic syndrome and diabetes. It correlates with the progression of chronic kidney disease, particularly with tubular atrophy. The fatty acid load on albumin significantly increases in obesity, presenting a proinflammatory environment to the proximal tubules. Howeve...

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Bibliografski detalji
Glavni autori: Ruggiero, Christine, Elks, Carrie M., Kruger, Claudia, Cleland, Ellen, Addison, Kaity, Noland, Robert C., Stadler, Krisztian
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989633/
https://ncbi.nlm.nih.gov/pubmed/24500687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00484.2013
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