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Saturated fatty acids bound to albumin enhance osteopontin expression and cleavage in renal proximal tubular cells

Osteopontin (OPN) is one of the proinflammatory cytokines upregulated in the kidneys of diabetic animals and patients with nephropathy. An increase in urinary albumin and albumin-bound fatty acids (FA) presents a proinflammatory environment to the proximal tubules in proteinuric kidney diseases incl...

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Detalhes bibliográficos
Publicado no:Int J Physiol Pathophysiol Pharmacol
Main Authors: Cobbs, Alyssa, Ballou, Kristopher, Chen, Xiaoming, George, Jasmine, Zhao, Xueying
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871627/
https://ncbi.nlm.nih.gov/pubmed/29593848
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