E2∼Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis

Pathogenic bacteria introduce effector proteins directly into the cytosol of eukaryotic cells to promote invasion and colonization. OspG, a Shigella spp. effector kinase, plays a role in this process by helping to suppress the host inflammatory response. OspG has been reported to bind host E2 ubiqui...

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Autores principales: Pruneda, Jonathan N, Smith, F Donelson, Daurie, Angela, Swaney, Danielle L, Villén, Judit, Scott, John D, Stadnyk, Andrew W, Le Trong, Isolde, Stenkamp, Ronald E, Klevit, Rachel E, Rohde, John R, Brzovic, Peter S
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989626/
https://ncbi.nlm.nih.gov/pubmed/24446487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386386
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