The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes

Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion system to inject effector proteins into host cells and induce their entry into epithelial cells or trigger apoptosis in macrophages. We present evidence that the effector OspG is a protein kinase that...

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Hlavní autoři: Kim, Dong Wook, Lenzen, Gerlinde, Page, Anne-Laure, Legrain, Pierre, Sansonetti, Philippe J., Parsot, Claude
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236552/
https://ncbi.nlm.nih.gov/pubmed/16162672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504466102
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