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The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes

Bacteria of Shigella spp. are responsible for shigellosis in humans. They use a type III secretion system to inject effector proteins into host cells and induce their entry into epithelial cells or trigger apoptosis in macrophages. We present evidence that the effector OspG is a protein kinase that...

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Detalhes bibliográficos
Main Authors: Kim, Dong Wook, Lenzen, Gerlinde, Page, Anne-Laure, Legrain, Pierre, Sansonetti, Philippe J., Parsot, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236552/
https://ncbi.nlm.nih.gov/pubmed/16162672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504466102
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