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OspF and OspC1 Are Shigella flexneri Type III Secretion System Effectors That Are Required for Postinvasion Aspects of Virulence

Shigella flexneri is the causative agent of dysentery, and its pathogenesis is mediated by a type III secretion system (T3SS). S. flexneri secretes effector proteins into the eukaryotic cell via the T3SS, and these proteins usurp host cellular functions to the benefit of the bacteria. OspF and OspC1...

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Detalhes bibliográficos
Main Authors: Zurawski, Daniel V., Mitsuhata, Chieko, Mumy, Karen L., McCormick, Beth A., Maurelli, Anthony T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594884/
https://ncbi.nlm.nih.gov/pubmed/16988276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00594-06
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