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OspF and OspC1 Are Shigella flexneri Type III Secretion System Effectors That Are Required for Postinvasion Aspects of Virulence

Shigella flexneri is the causative agent of dysentery, and its pathogenesis is mediated by a type III secretion system (T3SS). S. flexneri secretes effector proteins into the eukaryotic cell via the T3SS, and these proteins usurp host cellular functions to the benefit of the bacteria. OspF and OspC1...

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Autors principals: Zurawski, Daniel V., Mitsuhata, Chieko, Mumy, Karen L., McCormick, Beth A., Maurelli, Anthony T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594884/
https://ncbi.nlm.nih.gov/pubmed/16988276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00594-06
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