Shigella flexneri T3SS effectors OspB and OspF target the nucleus to down-regulate the host inflammatory response via interactions with retinoblastoma protein

OspF, OspG, and IpaH(9.8) are type III secretion system (T3SS) effectors of Shigella flexneri that down-regulate the host innate immune response. OspF modifies mitogen-activated protein kinase (MAPK) pathways and polymorphonuclear leukocyte (PMN) transepithelial migration associated with Shigella in...

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Autores principales: Zurawski, Daniel V., Mumy, Karen L., Faherty, Christina S., McCormick, Beth A., Maurelli, Anthony T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783611/
https://ncbi.nlm.nih.gov/pubmed/19017275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06524.x
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