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Shigella flexneri T3SS effectors OspB and OspF target the nucleus to down-regulate the host inflammatory response via interactions with retinoblastoma protein
OspF, OspG, and IpaH(9.8) are type III secretion system (T3SS) effectors of Shigella flexneri that down-regulate the host innate immune response. OspF modifies mitogen-activated protein kinase (MAPK) pathways and polymorphonuclear leukocyte (PMN) transepithelial migration associated with Shigella in...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783611/ https://ncbi.nlm.nih.gov/pubmed/19017275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06524.x |
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