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Ubiquitin in Motion: Structural studies of the E2~Ub conjugate

Ubiquitination of proteins provides a powerful and versatile post-translational signal in the eukaryotic cell. The formation of a thioester bond between ubiquitin (Ub) and the active site of a ubiquitin-conjugating enzyme (E2) is critical for Ub transfer to substrates. Assembly of a functional ubiqu...

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Bibliographic Details
Main Authors: Pruneda, Jonathan N., Stoll, Kate E., Bolton, Laura J., Brzovic, Peter S., Klevit, Rachel E.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056393/
https://ncbi.nlm.nih.gov/pubmed/21226485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101913m
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