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Structural Insights into the Conformation and Oligomerization of E2~Ubiquitin Conjugates

Post-translational modification of proteins by ubiquitin (Ub) regulates a host of cellular processes including protein quality control, DNA repair, endocytosis and cellular signaling. In the ubiquitination cascade, a thioester-linked conjugate between the Ub C-terminus and the active site cysteine o...

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Detalhes bibliográficos
Main Authors: Page, Richard C., Pruneda, Jonathan N., Amick, Joseph, Klevit, Rachel E., Misra, Saurav
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366460/
https://ncbi.nlm.nih.gov/pubmed/22551455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300058m
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