IL-27, targeting antigen presenting cells, promotes Th17 differentiation and colitis in mice

Th17 cells have been implicated in autoimmunity and inflammatory bowel disease (IBD). Antigen presenting cell (APC) derived cytokines such as IL-1β and IL-6 are key mediators supporting Th17 differentiation, yet how these factors are induced in vivo remains unclear. Here we show that IL-27 acting on...

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Detaylı Bibliyografya
Asıl Yazarlar: Visperas, Anabelle, Do, Jeongsu, Bulek, Katarzyna, Li, Xiaoxia, Min, Booki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989480/
https://ncbi.nlm.nih.gov/pubmed/24129161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.82
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