Gene Silencing Associated with SWI/SNF Complex Loss During NSCLC Development

The SWI/SNF chromatin-remodeling complex regulates gene expression and alters chromatin structures in an ATP-dependent manner. Recent sequencing efforts have shown mutations in BRG1 (SMARCA4), one of two mutually exclusive ATPase subunits in the complex, in a significant number of human lung tumor c...

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Detalhes bibliográficos
Main Authors: Song, Shujie, Walter, Vonn, Karaca, Mehmet, Li, Ying, Bartlett, Christopher S., Smiraglia, Dominic J., Serber, Daniel, Sproul, Christopher D., Plass, Christoph, Zhang, Jiren, Hayes, D. Neil, Zheng, Yanfang, Weissman, Bernard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989415/
https://ncbi.nlm.nih.gov/pubmed/24445599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0427
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