Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

The serine protease granzyme B, which is secreted by cytotoxic cells, is one of the major effectors of apoptosis in susceptible targets. To examine the apoptotic mechanism of granzyme B, we have analyzed its effect on purified proteins that are thought to be components of death pathways inherent to...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Quan, L T, Tewari, M, O'Rourke, K, Dixit, V, Snipas, S J, Poirier, G G, Ray, C, Pickup, D J, Salvesen, G S
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.1972
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